Drugs list > Dantroleno


Dantroleno is medication used for relaxing muscles in order to relieve tension. Mainly used for treating symptoms associated with stroke, cerebral palsy, disseminated sclerosis, and spinal injuries like cramps, muscle spasms, and general tightness, Dantroleno is not a cure for these conditions. Since symptoms are addressed, there is improvement in the condition of the patient, most especially when Dantroleno is used in conjunction with other kinds of treatment like physical therapy.

Dantroleno action

Dantroleno is useful also in addressing malignant hyperthermia, a condition that occurs after surgery or after anesthesia is administered where the patient experiences breathing problems, arrhythmia, and extremely high fever. Known as Dantroleno in Northern America and Dantrolen in European areas, this medication is marketed by Procter & Gamble and comes available as oral capsules or as injectables in vials.

For malignant hyperthermia, Dantroleno is administered intravenously, taking care of symptoms like muscle contractions, spasms, and cramps. Other symptoms that may be treated by intravenous Dantroleno include arrhythmia, unusually fast breathing, and elevated levels of carbon dioxide in the blood.

Dantroleno in capsules can be used for treating stiffness in the muscles and pain that are the result of conditions like disseminated sclerosis and cerebral palsy. Doctors may also prescribe Dantroleno capsules for treating high fevers.

Dantroleno dosage

Dantroleno capsules are usually taken once a day initially, with doses increasing to two to four times in a day. If you are having trouble swallowing capsules, the contents may be dissolved in some juice to facilitate intake of the medication. Dantroleno needs to be taken exactly as prescribed by your doctor and you must read included literature. You may be advised to stop taking Dantrolen if the medication is not showing results within 45 days.

If Dantroleno is used before an operation to specifically prevent potential malignant hyperthermia, the dose of the medication to be used depends often on the body weight of the patient at 4mg to 8mg per kilogram of weight per day distributed into three to four doses a day or two before the surgery. The last dose right before the surgery must be given at least three to four hours prior with some water.

If Dantroleno is being used intravenously to treat sudden-onset malignant hyperthermia, rapid dosage is advised. Start with a 1mg of Dantroleno for every kilogram of body weight, increasing dosage up to a maximum of 10mg per kilogram of body weight until the symptoms have subsided. Post-malignant hyperthermia doses can be given either orally or intravenously following similar doses but always with the advice from the doctor.

Dantroleno side effects

Side effects of using Dantroleno may include stomach disorders like constipation or diarrhea, dizziness, or general lethargy. Other less common side effects that may require medical attention include arrhythmia, abnormal hair growth, depression, rashes, hypersensitivity, and problems with urination.

Dantroleno may also cause severe liver problems in certain cases. Severe side effects normally occur when the medication is taken in large doses exceeding 800mg each day. Women over the age of 35 are also at greater risk of liver damage. If no improvement is seen, use of Dantroleno must be discontinued. Make sure you tell your doctor immediately if you start experiencing any of these symptoms: jaundice, unusual lethargy, extreme abdominal or stomach pain, and passing urine that is dark-colored.

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